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Can new immunoassay techniques improve bladder cancer diagnostics With protein biomarkers?

2021

The search for new diagnostic tests for cancer or ways to improve existing tests is primarily driven by the desire to identify the disease as early as possible. In this report, we summarize the current knowledge of the most promising diagnostic protein bladder cancer (BC) markers reported over the last decade. Unfortunately, analysis of published data suggests that a reliable, highly sensitive biomarker test-system based on ELISA for detecting BC has not yet been developed. The use of more sensitive assays to detect ultra-low concentrations of biomarkers not available for ELISA, could be very beneficial. Based on the literature and pilot experimental data, we conclude that a highly sensitiv…

0301 basic medicinemagnetic labelsMicroarrayProtein biomarkersComputational biologyBiochemistry Genetics and Molecular Biology (miscellaneous)Biochemistry03 medical and health sciences0302 clinical medicinemedicineMolecular Biosciencesimmunoassaylcsh:QH301-705.5Molecular BiologyBladder cancermedicine.diagnostic_testbusiness.industryCancerDiagnostic testprotein biomarkersmedicine.diseaseHighly sensitive030104 developmental biologylcsh:Biology (General)030220 oncology & carcinogenesisImmunoassayPerspectivebladder cancerBiomarker (medicine)businessmicroarrayFrontiers in Molecular Biosciences
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